Design, synthesis and application of carbazole macrocycles in anion sensors

• Alo Rüütel,
• Ville Yrjänä,
• Sandip A. Kadam,
• Indrek Saar,
• Mihkel Ilisson,
• Astrid Darnell,
• Kristjan Haav,
• Tõiv Haljasorg,
• Lauri Toom,
• Johan Bobacka and
• Ivo Leito

Beilstein J. Org. Chem. 2020, 16, 1901–1914, doi:10.3762/bjoc.16.157

• titrations were used to quantify binding in DMSO-d6/H2O solvent systems of two proportions – 99.5%:0.5% m/m and 90.0%:10.0% m/m, suggesting initial selectivity towards acetate. Three ionophores were selected for successful sensor prototype development and characterization. The constructed ion-selective

• sensor development, the results obtained in this work emphasize the importance of evaluating the binding behavior of receptors in real sensor membranes. Keywords: anion sensors; carboxylates; ionophores; macrocycles; sensor prototype; Introduction In 2013, Otto S. Wolfbeis asked the supramolecular

• recognition elements of chemical sensors. However, the research typically ended with demonstration of the ability of analyte binding. Rarely have the receptors found their way into functioning chemical sensor prototypes. The reason for this is that the step from a well-binding receptor to a sensor prototype